Part 2: The Wisdom of Healing in History – Traditional Medicinal Uses of Centella asiatica

 

Part 2: The Wisdom of Healing in History – Traditional Medicinal Uses of Centella asiatica

2.1. Introduction: The Healing Power of Centella asiatica Through Millennia

Centella asiatica is no ordinary plant. It is a medicinal herb that has journeyed alongside human history, treasured across diverse cultures for treating illness and promoting health. From the medical texts of ancient civilizations to the folk remedies passed down through generations, this plant has shared its life force with humanity.

In this chapter, we will trace the fascinating footsteps of Centella asiatica through the annals of traditional medicine—from Ayurveda in the East and Traditional Chinese Medicine to the vibrant folk practices of Southeast Asia and the hidden wisdom of the African continent. This historical exploration will serve as an excellent guide for modern science as it shines a new light on the efficacy of this remarkable herb.

2.2. Indian Ayurveda: "The Herb of Longevity and Wisdom," Mandukaparni and Brahmi

In Ayurveda, the traditional medicine of India, Centella asiatica has been regarded as a vital herb for thousands of years. It is primarily known as 'Mandukaparni' and sometimes as 'Brahmi'.

The name 'Brahmi' signifies an herb that bestows the wisdom of 'Brahman,' the creator god in Hinduism, specifically emphasizing its positive effects on the nervous system and brain function. Another theory suggests the name 'Mandukaparni' comes from the resemblance of its leaves to the webbed feet of a frog (Manduka). In Ayurveda, it is classified as a 'Medhya Rasayana'—a substance that enhances cognitive function, revitalizes the body and mind, and promotes youthfulness.

The long history of Centella asiatica is profound enough to be recorded in the ancient Indian medical text, the 'Sushruta Samhita'. The mention of this herb in such a significant text, believed to have been compiled before the common era, indicates that its medicinal properties were widely recognized and utilized on the Indian subcontinent thousands of years ago.

In Ayurveda, Centella asiatica is known for the following uses:

• Brain Health and Cognitive Enhancement: Widely used as a 'brain tonic' for its remarkable ability to improve memory, enhance concentration, boost learning capabilities, and calm the nerves. It was also a key herb in treating mental and nervous system disorders like depression, epilepsy, and hysteria.
• Skin Diseases and Wound Healing: It was effectively used to promote the healing of chronic skin conditions such as leprosy, lupus, eczema, and psoriasis, as well as common wounds and burns. This is attributed to its powerful cell-regenerating and anti-inflammatory properties.
• Other Benefits: Additionally, it was used to purify the blood, regulate high blood pressure, and alleviate symptoms like diarrhea and fever. It was also utilized in treating female genitourinary disorders and valued as a 'Rasayana' for overall health promotion and longevity.

As such, in Ayurveda, Centella asiatica was revered not only for physical healing but also as a crucial herb for mental clarity and a long life, and this traditional wisdom serves as a vital starting point for modern research.

2.3. Traditional Chinese Medicine (TCM): "The Herb that Clears the Blood," Ji Xue Cao (積雪草)

In Traditional Chinese Medicine (TCM), Centella asiatica has also been used as an important medicinal ingredient for a long time. In China, it is primarily called 'Ji Xue Cao' (積雪草). There are several theories about the origin of this name. It might signify its robust vitality, thriving even in cold environments with accumulated snow (雪, xuě), or it could stem from its ability to make the skin as white and clear as snow.

The use of Ji Xue Cao is first recorded in the 'Shennong Ben Cao Jing' (神農本草經), known as China's oldest pharmacological text. Its inclusion in this ancient classic, attributed to the legendary Shennong, suggests that its use in China dates back thousands of years. Subsequent major medical texts, including the 'Bencao Gangmu' (本草綱目) compiled by Li Shizhen during the Ming Dynasty, provide detailed descriptions of its form, ecology, and various efficacies. The 'Bencao Gangmu' notes that it grows in damp, shaded places in the south, has a bitter taste and a cold nature, and was used for conditions like acute conjunctivitis, various skin diseases, and fevers.

In TCM, Ji Xue Cao is known for these primary functions:

• Clearing Heat and Draining Dampness (淸熱利濕) & Detoxifying and Reducing Swelling (解毒消腫): It was believed to cool the body, eliminate dampness, neutralize toxins, and reduce swelling. This became the basis for its widespread use in treating inflammatory and infectious diseases.
• Treating Skin Diseases and Trauma: It was effectively used not only for inflammatory skin conditions like eczema, psoriasis, and rashes but also for treating wounds, burns, and boils, which relates to its anti-inflammatory and tissue-regeneration effects.
• Treating Other Illnesses: It was used for a wide range of conditions from common infections like colds, fevers, and sore throats to improving liver function in jaundice, promoting urination, and treating digestive issues like diarrhea and dysentery. Its ability to clear the mind and calm the spirit is also mentioned, indicating its use for enhancing brain health.

Thus, in TCM, Ji Xue Cao played a crucial role in correcting bodily imbalances and treating various diseases. This wisdom continues to this day, providing valuable inspiration for modern research and application of Centella asiatica.

2.4. The Wisdom of Southeast Asia: Bridging Daily Life and Medicine

In many Southeast Asian countries, Centella asiatica is a familiar plant deeply integrated into daily life and an important traditional medicine. Within each country's unique culture and environment, it is known by various names and used in diverse ways.

• Indonesia - Daun Kaki Kuda / Pegagan and Jamu: In Indonesia, it is called 'Daun Kaki Kuda' or 'Pegagan.' 'Daun Kaki Kuda' means 'horse hoof leaf,' a name derived from the unique shape of its leaves. It is a key ingredient in 'Jamu,' Indonesia's traditional herbal drink and medicine. Jamu containing Centella asiatica has been primarily used to alleviate hypertension, improve skin conditions, and resolve indigestion. Besides being used in drinks, it is consumed in foods like the traditional Acehnese salad 'sambai oi peuga-ga' or the Bogor-style 'asinan'. For skin ailments, a topical remedy of crushed fresh leaves applied directly to the affected area has also been traditionally used.

• Malaysia - Pegaga: In Malaysia, Centella asiatica is known as 'Pegaga' and is popularly consumed as a key ingredient in a traditional fresh salad called 'Ulam.' Ulam is considered more than just food; it's part of a wise dietary habit for maintaining health. Medicinally, it is used to promote skin health, accelerate wound healing, improve digestion, aid in detoxification, and enhance memory and mental clarity.

• Vietnam - Rau Má: In Vietnam, it is called 'Rau Má' and is an extremely popular health food ingredient. A juice made from grinding fresh Rau Má leaves is a representative health drink enjoyed by all ages, known for its effectiveness in cooling the body and reducing heat. It is also used in salads and wraps. Traditionally, Rau Má has been used for various purposes including reducing fever, detoxification, promoting urination, enhancing skin beauty, and accelerating wound healing.

• Other Southeast Asian Countries: In countries like Thailand, Cambodia, and Myanmar, Centella asiatica is used in similar ways. It is called 'bua bok' in Thailand, 'trachiek kranh' in Cambodia, and 'min-kuabin' in Myanmar, primarily used in health drinks, fresh salads, or as a traditional remedy for various ailments, contributing to the health of local populations.

A distinctive feature in Southeast Asia is the deep integration of Centella asiatica with daily food culture, suggesting it is relatively safe for consumption and that regular intake can be expected to promote health. This concept of "food as medicine" provides significant inspiration for modern research in functional foods and nutraceuticals.

2.5. Africa's Hidden Medicinal Herb: The Use of Centella asiatica

Within the vast natural landscape of the African continent, Centella asiatica has long been a part of traditional medicine. Although detailed records are not as abundant as in Asia, its healing powers have been recognized and utilized in various regions.

In African traditional medicine, its use has been prominent in treating skin diseases. Methods of applying crushed leaves or extracts for wounds, burns, leprosy, and skin ulcers have been passed down. Based on its anti-inflammatory effects, it was used for various inflammatory conditions and has been recorded as an antipyretic (fever reducer) and diuretic. There are also reports of its use in treating neurological disorders such as epilepsy and some mental illnesses, indicating its broad range of applications.

Notably, in Madagascar, it is known by the local name 'Talapetraka' and has been traditionally used in cooking or as a key herb for treating digestive ailments. Madagascar is a major producer of Centella asiatica, and its plants are known for their high and stable content of active compounds, attracting attention from the modern pharmaceutical and cosmetic industries.

In Mauritius, records show its use in treating leprosy as early as 1852, with documented clinical use for skin lesions caused by leprosy starting in 1887. This suggests its effectiveness for skin diseases was noticed from a Western medical perspective at a relatively early stage.

Across West, East, and Southern Africa, Centella asiatica likely grew wild and was used traditionally. Although detailed information on specific tribal names or traditional preparations is scarce in currently available data, it is presumed to have played a significant role in folk remedies related to skin diseases and wound healing throughout tropical Africa.

2.6. Indirect Traces in Ancient Western Medicine

Within the provided sources, there is no direct and clear evidence that Centella asiatica was mentioned in the major medical texts of ancient Egypt, Greece, or Rome.

These ancient Western civilizations also actively used a variety of plants for medicinal purposes and left rich records on wound and skin disease treatments. However, considering that the plant's native range is primarily the tropical/subtropical regions of Asia and Africa, it is difficult to confirm its prominent role in ancient Western medical systems. While the possibility of indirect transmission of knowledge or the plant itself through trade and cultural exchange cannot be ruled out, its traditional use appears to be concentrated mainly in Asian and African cultures based on current evidence.

2.7. Part 2 Conclusion: The Timeless Value of Centella asiatica

We have explored how Centella asiatica has been wisely used for treating diseases and promoting health across diverse global cultures—from Indian Ayurveda and Traditional Chinese Medicine to the folk remedies of Southeast Asia and Africa. Starting with the common benefits of wound healing and skin health improvement, it has played various roles according to the needs of each culture, including calming the mind, enhancing cognitive function, and promoting blood circulation.

This historical experience and traditional knowledge, spanning thousands of years, are not mere relics of the past. They serve as a crucial foundation and a source of inspiration for modern science in exploring the amazing efficacy of Centella asiatica. As the traditionally observed effects are now being scientifically validated through the identification of their components and mechanisms of action, Centella asiatica is once again being recognized as a valuable resource for human health.

In the upcoming Part 3, we will take a deep dive into Centella asiatica through the eyes of modern science, examining its powerful active ingredients and how they produce their remarkable effects within our bodies.

Reference

• 1. Centella asiatica (L.) Urb. | Plants of the World Online | Kew Science

• 2. Centella asiatica - Wikipedia

• 3. 병풀 - 한반도의 생물다양성

• 4. 병풀 - 나무위키

• 5. Topical Application of Centella asiatica in Wound Healing: Recent ...

• 6. 신의 내린 '병풀'...만병통치약 '호랑이풀' - 제주도민일보

• 7. Tiger Grass - Centella Asiatica - Greengredients

• 8. All about Centella Asiatica. Let us introduce you “Tiger herb” - Wilden Herbals

• 9. folkency.nfm.go.kr

• 10. 병풀(적설초) 무엇인가? - jdm0777.com

• 11. Gotu Kola Extract: Benefits Of Tiger Grass - Learn Canyon

• 12. An ultimate guide on Centella asiatica extract: ingredient, origin and benefits in cosmetics

• 13. Gotu Kola: 10 Benefits, Side Effects, and More - Healthline

• 14. Pentacyclic Triterpenoids from the Medicinal Herb, Centella asiatica (L.) Urban - PMC

• 15. Review of medicinal properties of mandukaparni (Centella asiatica).

• 16. Pharmacological Review on Centella asiatica: A Potential Herbal Cure-all - PubMed Central

• 17. Centella asiatica (Mandukaparni) – GreenSpace

• 18. Morphological Description and Ethnobotanical Review of the Orphan Crop Myin-Hkwa (Centella asiatica L.) From Myanmar - Frontiers

• 19. Blog: Ji Xue Cao | Nature's skin saviour – Dermatology M Store

• 20. Herba Glechomae - Chinese Medicine Regulatory Office Department of Health

• 21. 337 병풀, 적설초 (Centella asiatica), 현대한의학으로 이해하기! (2021.09.02. 수정)

• 22. asean herbal & medicinal plants

• 23. Indonesian herbal medicine prevents hypertension-induced left ventricular hypertrophy by diminishing NADPH oxidase-dependent oxidative stress - PMC

• 24. Jamu: Natural Immune Booster & Anti-Inflammatory - Murex Dive Resorts

• 25. Jamu (Indonesian Turmeric Ginger Drink) - Simply Recipes

• 26. Indonesian herbal medicine prevents hypertension-induced left ventricular hypertrophy by diminishing NADPH oxidase-dependent oxidative stress | Oncotarget

• 27. (PDF) Indonesian herbal medicine prevents hypertension-induced left ventricular hypertrophy by diminishing NADPH oxidase-dependent oxidative stress - ResearchGate

• 28. Top Health Benefits Of Pegaga (Gotu Kola) You Should Know - Mega We care https://www.megawecare.com/good-health-by-yourself/nutrition/gotu-kola-pegaga-benefits

• 29. An overview of Centella asiatica and its therapeutic applications - ResearchGate

• 30. Centella asiatica | PPT - SlideShare https://www.slideshare.net/slideshow/centella-asiatica/55727211

• 31. Centella asiatica (L.) Urban: From Traditional Medicine to Modern Medicine with Neuroprotective Potential - PubMed Central https://pmc.ncbi.nlm.nih.gov/articles/PMC3359802/

• 32. Vietnamese herbs - Jackfruit Adventure

• 33. Sip Your Way to Wellness: Explore Our Collection of Herbal Teas for Health and Relaxation - THE RIKE

• 34. Morphological Description and Ethnobotanical Review of the Orphan Crop Myin-Hkwa (Centella asiatica L.) From Myanmar - ResearchGate

• 35. Centella asiatica for skin: Uses, safety, benefits, and more https://www.medicalnewstoday.com/articles/centella-asiatica-for-skin

• 36. 여성들의 영원한 로망 '깨끗한 피부', 자연성분 화장품으로 관리 - 우먼타임스

• 37. Traditional Medicines in Africa: An Appraisal of Ten Potent African Medicinal Plants - PMC

• 38. Centella asiatica - UEBT

• 39. Centella asiatica (Gotu kola) as a neuroprotectant and its potential role in healthy ageing

• 40. (PDF) EFFECT OF CENTELLA ASIATICA, ECLIPTA PROSTRATA AND OXALIS CORNICULATA ON CARDIOVASCULAR DISEASES - ResearchGate

• 41. A drug for all seasons: Medical and pharmacological history of aloe - ResearchGate

• 42. Textual Research on Dioscorides and De Materia Medica

• 43. 4500년 전에도 인류 괴롭힌 감기…이집트 상형문자로 기록 [노석조의 외설] - 조선일보

• 44. 고대 이집트 파피루스에서 발견한 해부학 기록과 근대 의학의 선구자 갈레노스 - 블로그

• 45. [데일리팜] 로마시대 융성했던 약학이 수도원으로 간 까닭은

• 46. Greek Doctors in Rome - Scilit

• 47. Centella asiatica in cosmetology - PMC

• 48. Madecassoside | C48H78O20 | CID 24825675 - PubChem

• 49. 마데카소사이드 - 쿠스

• 50. www.biomol.com